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(A) Number of squares crossed, (B) latency to first rear, and (C) number of rears for adult (11-14 week-old) control (wild-type: n=6; ROSA+/-: n=24; Nes-Cre+: n=23) and nV59M (n=14) littermates over a 300s period. Data are mean ± SEM. *** p<0.0001 (Mann-Whitney U-test).
