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Top panels feature granulomas stained for collagen I (red), TGF-β1 signaling (green), and macrophages (primary granuloma cell type) (blue). Bottom panels feature granulomas stained for activated TGF-β1 (red), latent TGF-β1 (green), and myofibroblasts (αSMA) (blue). Magnification ×200. A) Granuloma from an animal following two months of antibiotic treatment. B, C, D) Granulomas are from animals with active TB.
