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. Author manuscript; available in PMC: 2018 Sep 21.
Published in final edited form as: J Theor Biol. 2017 Jun 20;429:1–17. doi: 10.1016/j.jtbi.2017.06.017

Table 2.

Significant PRCC values for parameters driving cell number at day 300 PI. p < 0.01

Parameter Description PRCC p value
Fibroblast number
γ18 Degradation rate of active TGF-β1 0.15 1.82*10−5
μ18 Amount of TGF-β1 that inhibits macrophages −0.11 1.55*10−3
τ14 Bound TGF-β1 that inhibits T cells 0.10 4.04*10−3
τ12 Synthesis rate of TGF-β1 by regulatory T cell 0.09 9.49*10−3
ζ3 Probability a fibroblast will move 0.77 1.68*10−170
ζ7 Fibroblast IL10 proliferation threshold 0.13 1.67*10−4
ζ11 TNFα fibroblast proliferation threshold −0.09 5.66*10−3
ζ12 Synthesis rate of IL10 by fibroblast −0.10 3.96*10−3
ζ15 Fibroblast sensitivity to TGF-β1 0.09 8.64*10−3
Myofibroblast number
ζ3 Probability a fibroblast will move 0.17 1.08*10−6
ζ9 TGF-β1 fibroblast proliferation threshold −0.16 3.23*10−6
ζ8 TGF-β1 fibroblast differentiation threshold −0.21 4.41*10−10
ζ13 Fibroblast IL10 binding rate −0.13 1.00*10−4
ζ14 Fibroblast sensitivity to IL10 −0.36 1.52*10−28
ω3 Degradation rate of αSMA −0.42 5.16*10−39
Collagen concentration
ζ3 Probability a fibroblast will move 0.20 3.08*10−9
ζ9 TGF-β1 fibroblast proliferation threshold −0.16 1.12*10−6
ζ8 TGF-β1 fibroblast differentiation threshold −0.22 2.33*10−11
ζ13 Fibroblast IL10 binding rate −0.14 4.20*10−5
ζ14 Fibroblast sensitivity to IL10 −0.39 2.11*10−32
ω3 Degradation rate of αSMA −0.42 1.67*10−38