Skip to main content
. Author manuscript; available in PMC: 2018 Sep 21.
Published in final edited form as: J Theor Biol. 2017 Jun 20;429:1–17. doi: 10.1016/j.jtbi.2017.06.017

Table 3.

Significant PRCC values for parameters driving fibroblast number within a granuloma and on the periphery of a granuloma at day 300 PI. p < 0.01

Parameter Description PRCC p value
Fibroblasts within the granuloma
μ1 Fraction of grid compartments with a macrophage 0.11 3.13*10−5
μ19 Fraction of active TGF-β1 in a compartment bound by a mac 0.09 5.00*10−4
ζ3 Probability a fibroblast will move −0.12 4.91*10−6
ζ9 TGF-β1 fibroblast proliferation threshold 0.49 2.62*10−90
ζ11 TNFα fibroblast proliferation threshold 0.19 6.58*10−13
ω3 Degradation rate of αSMA 0.11 1.55*10−5
Fibroblasts on the periphery of the granuloma
γ10 Maximum number of molecules allowing chemotaxis −0.13 6.04*10−7
γ18 Degradation rate of active TGF-β1 0.12 5.43*10−6
μ1 Fraction of grid compartments with a macrophage 0.11 1.24*10−5
τ12 Synthesis rate of TGF-β1 by regulatory T cell 0.07 5.15*10−3
ζ3 Probability a fibroblast will move 0.69 2.46*10−205
ζ7 Fibroblast Il10 proliferation threshold 0.08 2.80*10−3
ζ11 TNFα fibroblast proliferation threshold −0.08 2.96*10−3