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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Brain Res. 2017 Jul 11;1672:10–17. doi: 10.1016/j.brainres.2017.07.003

Figure 4.

Figure 4

Potassium-evoked glutamate overflow in increased in the DG of DOX treat mice. (A) No differences in evoked glutamate overflow were evident following DOX treatment in the prefrontal cortex (n=7/group). (B) However, in the DG (Sal=7, DOX=8), glutamate overflow was significantly greater in DOX treated mice (*p<0.05). Statistical analysis was done using an unpaired 2-tailed Student's t-test. Error bars represent the mean ± SEM. (C) Representative raw traces of potassium-evoked glutamate release in the DG. The black arrows mark where KCl was locally applied to the DG. The hash marks (//) indicate where ∼100 seconds were removed to preserve space.