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. 2017 Aug 30;12(8):e0184046. doi: 10.1371/journal.pone.0184046

Table 3. H. pylori genes with higher expressiona in IDA strains.

Gene designation Gene name Expression ratio
and category Predicted function (IDA / control) p value
Cell envelope:
    HP0722 sabB (HopO) adhesin 10.9 < 0.001
    HP0725 sabA (HopP) adhesin 3.7 < 0.001
    HP0217 cgtA LPS synthesis 3.6 0.002
DNA metabolism:
    HP0142 mutY DNA repair 5.4 < 0.001
    HP0462 hsdS restriction system 7.3 < 0.001
    HP0463 hsdM restriction system 10.6 < 0.001
    HP0592 res restriction system 3.6 0.003
Cellular processes:
    HP0682 coaX CoA synthesis 84.0 0.003
    HP1510 folB folic acid synthesis 3.7 < 0.001
    HP1511 predicted frpB-like protein 3.6 < 0.001
Other categories:
    HP0428 terY phage/colicin 3.5 0.02
    HP0414 transposase A 4.3 0.018
    HP0731 leoA toxin production 3.9 < 0.001
    HP1000 partition protein A 6.0 < 0.001
Hypothetical proteins:
    HP0016 unknown 5.2 < 0.001
    HP0059 unknown 3.9 0.001
    HP0120 unknown 6.0 < 0.001
    HP0199 unknown 4.1 0.001
    HP0435 COG1112 superfamily DNA and RNA-helicase unknown 3.7 0.022
    HP0436 COG3843, virD2 unknown 5.9 0.015
    HP0489 unknown 3.6 0.03
    HP0583 unknown 4.5 < 0.001
    HP0999 unknown 4.6 0.021
    HP1116 unknown 3.5 0.047
    HP1165 tetA unknown 4.3 < 0.001
    HP1334 COG1432 unknown 3.8 < 0.001
    HP1371 type III restriction enzyme R protein unknown 4.1 0.001
    HP1388 unknown 4.2 0.036
    HP1589 COG4735 unknown 3.8 0.004

a As determined by microarray analysis (see Methods).