Table 3. H. pylori genes with higher expressiona in IDA strains.
Gene designation | Gene name | Expression ratio | |||
---|---|---|---|---|---|
and category | Predicted function | (IDA / control) | p value | ||
Cell envelope: | |||||
HP0722 | sabB (HopO) | adhesin | 10.9 | < 0.001 | |
HP0725 | sabA (HopP) | adhesin | 3.7 | < 0.001 | |
HP0217 | cgtA | LPS synthesis | 3.6 | 0.002 | |
DNA metabolism: | |||||
HP0142 | mutY | DNA repair | 5.4 | < 0.001 | |
HP0462 | hsdS | restriction system | 7.3 | < 0.001 | |
HP0463 | hsdM | restriction system | 10.6 | < 0.001 | |
HP0592 | res | restriction system | 3.6 | 0.003 | |
Cellular processes: | |||||
HP0682 | coaX | CoA synthesis | 84.0 | 0.003 | |
HP1510 | folB | folic acid synthesis | 3.7 | < 0.001 | |
HP1511 | predicted frpB-like protein | 3.6 | < 0.001 | ||
Other categories: | |||||
HP0428 | terY | phage/colicin | 3.5 | 0.02 | |
HP0414 | transposase A | 4.3 | 0.018 | ||
HP0731 | leoA | toxin production | 3.9 | < 0.001 | |
HP1000 | partition protein A | 6.0 | < 0.001 | ||
Hypothetical proteins: | |||||
HP0016 | unknown | 5.2 | < 0.001 | ||
HP0059 | unknown | 3.9 | 0.001 | ||
HP0120 | unknown | 6.0 | < 0.001 | ||
HP0199 | unknown | 4.1 | 0.001 | ||
HP0435 | COG1112 superfamily DNA and RNA-helicase | unknown | 3.7 | 0.022 | |
HP0436 | COG3843, virD2 | unknown | 5.9 | 0.015 | |
HP0489 | unknown | 3.6 | 0.03 | ||
HP0583 | unknown | 4.5 | < 0.001 | ||
HP0999 | unknown | 4.6 | 0.021 | ||
HP1116 | unknown | 3.5 | 0.047 | ||
HP1165 | tetA | unknown | 4.3 | < 0.001 | |
HP1334 | COG1432 | unknown | 3.8 | < 0.001 | |
HP1371 | type III restriction enzyme R protein | unknown | 4.1 | 0.001 | |
HP1388 | unknown | 4.2 | 0.036 | ||
HP1589 | COG4735 | unknown | 3.8 | 0.004 |
a As determined by microarray analysis (see Methods).