Table 1.
Characteristics of the block copolymers
| Polymer | Code | Sizea (Deff, nm) | PDI | Zeta potential (mV)a |
|---|---|---|---|---|
| PEG-b-PLL-b-PLA | TM | 94±4 | 0.18±0.03 | +18.1±0.7 |
| PEG-b-PLL(-g-Ce6)-b-PLAb | CTM | 112±14 | 0.22±0.02 | +12±2 |
| PEG-b-PLL(-g-Ce6, DMA)-b-PLAc | CDTM | 94±2.2 | 0.20±0.02 | −14±2.5 |
Notes:
Particle size, PDI, and zeta potential were measured using DLS equipment;
Molar ratio between l-lysine and Ce6 =15:1;
Molar ratio between l-lysine, Ce6, and DMA =15:1:9.
Abbreviations: CDTM, PEG-PLL(-g-Ce6 and DMA)-PLA micelles; Ce6, chlorin e6; CTM, PEG-PLL(-g-Ce6)-PLA micelles; Deff, effective hydrodynamic diameters; DLS, dynamic light scattering; DMA, 2,3-dimethyl maleic anhydride; PDI, polydispersity index; PEG, poly(ethylene glycol); PLA, poly(lactic acid); PLL, poly(l-lysine).