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. 2017 Aug 30;12(8):e0182454. doi: 10.1371/journal.pone.0182454

Fig 3. Experimental design and bone volume measurements.

Fig 3

Fig 3A. SCI: spinal cord injury; PNS: peripheral nervous system; CTX: cardiotoxin. T0: CTX was injected during surgery. D10: CTX was injected 10 days after surgery BV: HO Bone Volume measured with CT scan in right hind limb (RHL) versus left hind limb (LHL). Fig 3B. CT scan of harvested hind limbs showed bilateral intramuscular HO in one mouse from group 1 and 3 and no HO in mouse from group 2. Fig 3C. HO volumes in hind limbs of 6 mice from group 1 showing significant increased BV after peripheral denervation. Fig 3D. Amyotrophic right hind limb after peripheral denervation 28 days after surgery.