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Coal mine dust desquamative chronic interstitial pneumonia. Alveoli are filled by macrophages laden with anthracotic pigment and birefringent silica/silicate particles. There is no fibrosis in the upper panels. Mild fibrosis of the alveolar septum presents in the left lower corner of photomicrographs in the lower panel. On the left side are photomicrographs of H&E-stained tissue (original magnification 400×); on the right side are same frames under polarized light.
