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CRISPR-Cas9–mediated Sf-fdl gene editing for host engineering in the BICS. The bar graph shows the relative proportions of different N-glycan structures released from hEPO produced by Sf9, SfFDLt1 polyclonal population, and SfFDLt1 clone #32. These data are derived from the MALDI-TOF-MS profiles shown in Fig. S5 and represent the relative percentages of each N-glycan shown along the bottom of the figure as a percentage of total.
