Table 1. Organ Weights^a.

	low fat diet				high fat diet
		imidacloprid (mg/kg bw/day)				imidacloprid (mg/kg bw/day)			P-value
	control	0.06	0.6	6	control	0.06	0.6	6	dietary fat	imidacloprid	interaction
% of Body Weight
liver	4.04 ± 0.27	4.45 ± 0.35	4.56 ± 0.17	4.87 ± 0.25	3.45 ± 0.26	3.63 ± 0.16	3.79 ± 0.13	3.36 ± 0.15	<0.0001	n.s.	n.s.
heart	0.52 ± 0.02	0.54 ± 0.03	0.50 ± 0.01	0.48 ± 0.01	0.47 ± 0.03	0.46 ± 0.02	0.40 ± 0.02	0.42 ± 0.03	<0.0001	n.s.	n.s.
spleen	0.37 ± 0.03	0.43 ± 0.07	0.35 ± 0.01	0.36 ± 0.02	0.37 ± 0.04	0.31 ± 0.01	0.26 ± 0.01	0.29 ± 0.01	0.017	n.s.	n.s.
kidney	1.30 ± 0.06	1.31 ± 0.08	1.27 ± 0.02	1.19 ± 0.02	1.17 ± 0.05	1.15 ± 0.05	1.05 ± 0.03	1.09 ± 0.04	0.0002	n.s.	n.s.
pancreas	1.04 ± 0.09	1.06 ± 0.08	0.96 ± 0.04	0.93 ± 0.03	1.06 ± 0.16	0.93 ± 0.10	0.82 ± 0.05	0.85 ± 0.04	n.s.	n.s.	n.s.
Adipose Tissue
omental	3.00 ± 0.28c	2.82 ± 0.23c	2.60 ± 0.27c	3.34 ± 0.51bc	4.62 ± 0.38b	4.71 ± 0.69ab	6.69 ± 0.39a	6.63 ± 1.19a	<0.0001	0.010	0.0375
subcutaneous	2.45 ± 0.19abc	2.32 ± 0.17c	2.22 ± 0.24c	2.24 ± 0.39c	4.26 ± 0.41a	4.22 ± 0.68ab	5.89 ± 0.31a	5.69 ± 0.38a	<0.0001	n.s.	0.029
retroperitoneal	1.01 ± 0.13	0.91 ± 0.17	0.90 ± 0.13	1.34 ± 0.18	2.16 ± 0.21	2.10 ± 0.39	2.93 ± 0.16	2.82 ± 0.12	<0.0001	n.s.	n.s.
mesenteric	0.88 ± 0.15	0.80 ± 0.09	0.81 ± 0.12	1.07 ± 0.16	1.47 ± 0.16	1.50 ± 0.35	2.03 ± 0.19	1.80 ± 0.15	<0.0001	n.s.	n.s.
total	7.34 ± 0.85cd	6.85 ± 0.35d	6.53 ± 0.81d	7.99 ± 0.97bcd	12.5 ± 1.25b	10.0 ± 3.09bc	17.5 ± 1.06a	16.9 ± 1.08a	<0.0001	0.026	0.028

^aMice were treated with three doses of imidacloprid (0.06, 0.6, and 6 mg/kg bw/day). Values represent means ± SE (n = 5–7). Means with different superscripts within the same row are significantly different at P < 0.05. Abbreviations: n.s., not significant.