Table 2.
Risk factors for ESRD in living kidney donors
| Characteristic | aHRa | P Value |
|---|---|---|
| Men (at age 40) | 1.88 (95% CI, 1.50 to 2.35) | <0.001 |
| black race (at age 40) | 2.96 (95% CI, 2.25 to 3.89) | <0.001 |
| Age per 10 yr: nonblack | 1.40 (95% CI, 1.23 to 1.59) | <0.001 |
| Age per 10 yr: black | 0.88 (95% CI, 0.72 to 1.09) | 0.3 |
| BMI per 5 kg/m2 | 1.61 (95% CI, 1.29 to 2.00) | <0.001 |
| First-degree biologically related to recipient | 1.70 (95% CI, 1.24 to 2.34) | <0.01 |
a
Male sex and greater BMI were associated with higher risk of ESRD (both P<0.001). Older age was associated with higher risk of ESRD in nonblack male donors (P<0.001), but the association between age and risk was not statistically significant in black donors (P=0.1). Donors who were closely related to their recipient had higher risk of ESRD (P<0.01).