Table 3.
Cardiovascular and mortality events in the SPRINT participants with CKD
| Outcome | Intensive Treatment, n=1330 | Standard Treatment, n=1316 | Intensive Treatment Versus Standard Treatment | |||
|---|---|---|---|---|---|---|
| No. of events | Percent per 1 yr | No. of events | Percent per 1 yr | HR (95% CI) | P Value | |
| Primarya outcome | 112 | 2.68 | 131 | 3.19 | 0.81 (0.63 to 1.05) | 0.12 |
| Myocardial infarction | 44 | 1.03 | 45 | 1.07 | 0.94 (0.62 to 1.44) | 0.79 |
| Acute coronary syndrome | 15 | 0.35 | 11 | 0.26 | 1.35 (0.60 to 3.08) | 0.47 |
| Stroke | 27 | 0.63 | 27 | 0.64 | 0.99 (0.57 to 1.70) | 0.96 |
| Heart failure | 41 | 0.96 | 52 | 1.24 | 0.72 (0.47 to 1.10) | 0.13 |
| CVD death | 18 | 0.41 | 30 | 0.70 | 0.57 (0.31 to 1.02) | 0.06 |
| All-cause death | 70 | 1.61 | 95 | 2.21 | 0.72 (0.53 to 0.99) | 0.04 |
| Primary outcome or all-cause death | 152 | 3.62 | 179 | 4.35 | 0.82 (0.66 to 1.02) | 0.08 |
| Primary outcome or cardiovascular procedure | 127 | 3.06 | 161 | 3.98 | 0.81 (0.63 to 1.05) | 0.12 |
a
The sum of the individual components of the primary composite outcome is greater than the number of primary composite outcome events, because some participants experienced more than one component event.