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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: DNA Repair (Amst). 2017 Jun 9;56:51–64. doi: 10.1016/j.dnarep.2017.06.007

Figure 3. Maintenance of genomic integrity requires the integration of multiple factors for DNA repair in response to damage.

Figure 3

Mechanisms resulting in pathway crosstalk include the induction of functional protein-protein interactions (red) or PTMs (blue). A field that requires further analysis is how these individual areas intersect to result in pathway crosstalk, as illustrated by the overlap in the Venn diagram. Pathway crosstalk results in functional consequences that allow for a rapid and efficient DNA repair response to damage.