Table 2.
| Data | Pathway ID | Pathway name | Number of DE/original pathway genes | Drug target |
|---|---|---|---|---|
| GSE20566 | hsa03450 | Non-homologous end-joining | 4/13 | NA |
| hsa04750 | Inflammatory mediator regulation of TRP channels | 10/99 | HTR2A HRH1 PRKCE PRKCD PRKCA PRKCB PRKCG PRKCQ | |
| hsa04060 | Cytokine-cytokine receptor interaction | 26/265 | VEGFA TNFS11 PRLR EGFR | |
| hsa04360 | Axon guidance | 16/176 | PRKCA | |
| hsa05168 | Herpes simplex infection | 21/185 | JUN NFKB1 | |
| hsa04310 | Wnt signaling pathway | 20/144 | JUN PRKCA PRKCB PRKCG | |
| hsa04340 | Hedgehog signaling pathway | 7/48 | BCL2 | |
| hsa04070 | Phosphatidylinositol signaling system | 15/99 | PRKCA PRKCB PRKCG | |
| hsa05220 | Chronic myeloid leukemia | 11/73 | NFKB1 CDK4 CDK6 | |
| GSE20194 | hsa00330 | Arginine and proline metabolism | 3/52 | NA |
| hsa04974 | Protein digestion and absorption | 2/90 | NA | |
| hsa04810 | Regulation of actin cytoskeleton | 7/216 | EGFR CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 | |
| hsa05010 | Alzheimer’s disease | 9/171 | MAPT | |
| hsa00010 | Glycolysis/Gluconeogenesis | 5/67 | NA |
Note: NA denotes not found.