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. 2017 Aug 30;7:10021. doi: 10.1038/s41598-017-10602-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Schematic of the steps undertaken in this study. A Fix for Life cadaver head was used to identify alar cartilage on MRI. 3T MRI was used to identify the MRI sequence that provided the best visualization for alar cartilage segmentation. The right alar cartilage was dissected from the cadaveric head and scanned using micro-CT. The resulting images were then processed in imaging software (see Fig. 5) for additive manufacturing. 3T MRI, Image processing, and additive manufacturing were repeated in a volunteer (squared boxes). 3T, 3 Tesla; micro-CT, micro-Computed Tomography.