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. 2017 Aug 30;7:10095. doi: 10.1038/s41598-017-09319-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Meta-regression results showed that the mean age (a) and BMI (b) of patients with OSA were positively correlated with gray matter in the bilateral ACG/ApCG and that the ESS scores of patients with OSA (c) and the percentages of male patients with OSA (d) were negatively correlated with gray matter in the bilateral SFG (medial rostral part). The effect sizes in this graph were extracted from the peak of maximum slope significance, and the dot size reflects the sample size of each study. Abbreviations: ACG/ApCG, anterior cingulate/paracingulate gyri; SFG, superior frontal gyrus.