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. 2017 Aug 30;7:9593. doi: 10.1038/s41598-017-10109-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Classification of sIgE positive reactivity for individual allergens in Guangdong (A) and Yunnan (B) (%). Regarding the severity for individual allergens in both regions, the majority of allergens caused low-level sIgE reactivity (Classes 1–2) except for d1 which caused high-class reactivity (≥class 4 or above) in 41.9% of d1-positive Guangdong subjects. d1: house dust mite; i6: cockroach; tx4: tree pollen mix; mx1: mold mix; e5: dog dander; f23: crab; f24: shrimp; f1: egg white; f2: milk.