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. 2017 Aug 30;7:9972. doi: 10.1038/s41598-017-10605-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Genotypes of eight gene segments of H7N9 influenza A viruses from Feb 2013 to Jan 2017. Figure 2 shows genotype models of chicken and human strains with HP characteristics. Red squares indicate genes belonging to the Yangtze River Delta clade, blue squares represent genes of the Pearl River Delta clade and green squares represent genes belonging to clade from other regions. Abbreviations: YRD (Yangtze River Delta), PRD (Pearl River Delta), OR (other regions); W1, W2, W3, W4 and W5 (1^st to 5^th wave H7N9 epidemics, respectively). PB2 (polymerase basic protein 2 gene), PB1 (polymerase basic protein 1 gene), PA (polymerase acidic protein gene), HA (hemagglutinin gene), NP (nucleoprotein gene), NA (neuraminidase gene), M (matrix protein gene), and NS (non-structural protein). CK/J1(A/Chicken/Guangdong/J1/2017), CK/J2(A/Chicken/Guangdong/J2/2017), QY/GIRD1(A/Qingyuan/GIRD1/2017), GD/SP440(A/Guangdong/SP440/2017), GD/HP001(A/Guangdong/HP001/2017), GD/17SF003(A/Guangdong/17SF003/2016), GD/17SF006(A/Guangdong/17SF006/ 2017) and SH/1(A/Shanghai/1/2013).