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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Med Decis Making. 2017 May 10;37(7):802–814. doi: 10.1177/0272989X17706081

Table A-4.

Risk adjustment based on Treatment (Relative Risk Reduction)

Parameter Base Case Value Sensitivity Analysis Value Source
Relative Risk in the Primary Prevention
Statin
 CHD 0.75 0.71–0.78 Baigent 2005 (30)
 Stroke 0.83 0.76–0.87 Baigent 2005 (30)
Aspirin
 CHD 0.82 0.75–0.9 ATT Collaboration 2009 (56)
 Stroke 0.95 0.85–1.06 ATT Collaboration 2009 (56)
Blood Pressure Treatment
 CHD 0.84 0.79–0.9 Law 2009 (57)
 Stroke 0.64 0.56–0.73 Law 2009 (57)

Relative Risk in the Secondary Prevention
Statin
 Death 0.88 0.84–0.92 Cholesterol Treatment Trialists 2012 (31)
 MI 0.76 0.73–0.79 Cholesterol Treatment Trialists 2012 (31)
 Stroke 0.85 0.81–0.9 Cholesterol Treatment Trialists 2012 (31)
Aspirin
 Death 0.91 0.82–1.00 ATT Collaboration 2009 (56)
 MI 0.69 0.6–0.8 ATT Collaboration 2009 (56)
 Stroke 0.81 0.71–0.92 ATT Collaboration 2009 (56)
ACE Inhibitor
 Death 0.87 0.81–0.94 Baker 2009 (29)
 MI 0.83 0.73–0.94 Baker 2009 (29)
 Stroke 0.78 0.63–0.97 Baker 2009 (29)
Beta Blocker
 Death 0.94 0.79–1.10 Lindholm 2005 (32)
 MI 0.89 0.74–1.06 Lindholm 2005 (32)
 Stroke 0.84 0.64–1.10 Lindholm 2005 (32)