Table 4.
Newborn lambs’ arterial blood gases, mean arterial blood pressure (MABP), heart rate (HR) together with EEG and NIRS data obtained before and during the induced hypercapnia (values are means ± SEM, n = 7 lambs)
| Before hypercapnia | During hypercapnia | |
|---|---|---|
| pH | 7.38 ± 0.03 | 7.18 ± 0.02*** |
| (mmHg) | 40.4 ± 1.4 | 65.8 ± 2.3*** |
| (mmHg) | 95.2 ± 4.5 | 138.8 ± 21.2 |
| HCO3 − (mmol l−1) | 23.1 ± 1.4 | 23.9 ± 1.3 |
| BE (mmol l−1) | −1.5 ± 1.6 | −4.5 ± 1.4*** |
| Glucose (mmol l−1) | 9.7 ± 1.2 | 9.4 ± 0.9 |
| Lactate (mmol l−1) | 1.2 ± 0.1 | 0.8 ± 0.1** |
| MABP (mmHg) | 70.0 ± 5.8 | 60.2 ± 4.9** |
| HR (beats min−1) | 208.6 ± 12.0 | 218.5 ± 12.5* |
| Amplitude of SEP(N/P50) (ms) | 43.4 ± 13.1 | 41.8 ± 9.9 |
| Latency of SEPs (N/P50) (μV) | 7.9 ± 2.9 | 8.1 ± 1.6 |
| Total Hb (μm cm) | −0.4 ± 1.2 | 307.7 ± 68.1** |
| OxyHb (μm cm) | 2.7 ± 2.1 | 340.4 ± 54.8*** |
| DeoxyHb (μm cm) | −3.1 ± 2.1 | −32.7 ± 17.3 |
ΔDeoxyHb, change in deoxyhaemoglobin; ΔOxyHb, change in oxyhaemoglobin; ΔTotal Hb, changes in total haemoglobin; SEP, somatosensory evoked potential. * P < 0.05 vs. before hypercapnia; ** P < 0.01 vs. before hypercapnia; *** P < 0.001 vs. before hypercapnia.