Table 2.
13C-NMR chemical shifts (ppm) observed for non-modified Alg, 4-ASA, and Alg-4-ASA (1:1) amide conjugate.
| Assignment (δ ppm) | Na-Alg | 4-ASA | Alg-ASA (1:1) |
|---|---|---|---|
| C-1 MM | 102.7 | NA | 102.5 |
| C-2 MM | 72.3 | NA | 72.7 |
| C-3 MM | 72.8 | NA | 71.3 |
| C-4 MM | 79.3 | NA | 77.2 |
| C-5 MM | 77.3 | NA | 72.8 |
| C-6 MM | 176.5 | NA | 176.5 |
| C-1 GG | 101.4 | NA | 101.4 |
| C-2 GG | 66.2 | NA | 63.9 |
| C-3 GG | 71.5 | NA | 67.5 |
| C-4 GG | 81.5 | NA | 79.3 |
| C-5 GG | 68.9 | NA | 65.7 |
| C-6 GG | 177.2 | NA | 176.5 |
| C-1′ | NA | 109.7 | 110.3 |
| C-2′ | NA | 131.2 | 131.5 |
| C-3′ | NA | 109.7 | 110.3 |
| C-4′ | NA | 151.5 | 155.4 |
| C-5′ | NA | 103.3 | 104.4 |
| C-6′ | NA | 158.7 | 156.8 |
| C-7′ | NA | 169.6 | 166.1 |
NA = Not applicable.