Representative PET images of normal and tumor-bearing aged, retired breeding rats 1 h after injection with 64Cu-DOTA-alendronate. (A) Normal mammary gland (white arrow) (SUV, 0.3). (B) Mammary fibroadenoma (pink arrow) (SUV, 0.74). (C) Mammary carcinoma (green arrow) (SUV, 2.0) with intense calcification foci (blue arrow) (SUV, 4.4).