Table 3.
Intraoperative sedation, primary analgesic outcomes, and other secondary hemodynamic outcomes in the operated breast cancer patients receiving paravertebral block*
| Outcomes | No. (%) of patients |
P | |
|---|---|---|---|
| LG group (n = 40) | LLG group (n = 40) | ||
|
Intraoperative sedation |
|||
| Continuous doses of 1% propofol (µg/kg/min; median, 95% CI) |
65.0 (60.0-70.0) |
70.0 (70.0-80.0) |
0.088† |
|
Primary analgesic outcomes |
|||
| Time-to-block onset (minutes; median, 95% CI) |
37.0 (36.0-40.0) |
23.0 (20.0-25.0) |
<0.001† |
| Duration of analgesia (minutes; median, 95% CI) |
490.0 (460.0-520.0) |
385.0 (350.0-460.0) |
0.006† |
|
Other secondary hemodynamic outcomes |
|||
| Intraoperative crystalloids (mL; median, 95% CI) |
600.0 (600.0-700.0) |
1150.0 (1000.0-1300.0) |
<0.001† |
| Episodes of hypotension |
2 (5.0) |
9 (22.5) |
0.048‡ |
| Ephedrine hydrochloride, 5 mg iv. |
2 (5.0) |
7 (17.5) |
0.154‡ |
| Atropine sulfate, 0.5 mg iv. | 0 (0) | 3 (7.5) | 0.241‡ |
*Abbreviations: LG – 0.5% levobupivacaine; LLG – 0.5% levobupivacaine + 2% lidocaine; CI – confidence interval.
†Mann-Whitney U test.
‡Fisher exact test.