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. 2017 May 16;20(Suppl 3):21490. doi: 10.7448/IAS.20.4.21490

Table 1.

Clinical Outcomes Following HIV Health Care Transition in the Medical Literature.

Study [Ref] (Region) Population Median age at Transfer (years) Post-HCT Retention Post-HCT
cART Adherence
Post-HCT
HIV Suppression
Post-HCT
CD4 Change
Post-HCT Mortality
Maturo, 2015 [17] (US) N=38 BA-HIV NA 18 (47%) completed transfer to adult careb NA NA NA NA
Fish, 2014 [60] (UK) N=14, PA-HIV 17 NA At transfer:
64% taking HAART
At death:
36% taking HAART
14% with documented suppression at last evaluation At transfer: median CD4: 120 cells/uL
At death: median CD4: 27 cells/uL
100% (by study design)
Ryscavage, 2016 [42] (US) N=50
19 PA-HIV
31-BA-HIV
24.5 50%a NA Pre-transfer: 36%
Post-transfer: 57% (p=NS)
Pre-transfer: 347 cells/uL
Post-transfer: 351 cells/uL
0%
Hope, 2016 [61] (UK) N=211 PA-HIV 17.6 88% NA Pre-transfer: 43%
Post-transfer: 63% (p=<.001)
Pre-transfer: 450 cells/uL
Post-transfer: 420 cells/uL *Rate of decline decreased post transfer
4.3%
Righetti, 2015
[62] (Italy)
N=45 8.8 84%b NA Post-transfer: 73% NA NA
Kakkar, 2016 [59] (Canada) N=45 PA-HIV
(25 consented to study)
18 76%c 60% reported less than “excellent” adherence Pre-transfer: 60% Pre-transfer: CD4>500 cells/uL: 41%Post-transfer: CD4>500 cells/uL: 29% 8.9%
Weijsenfeld, 2016 [11]
(Netherlands)
N=59
78% PA-HIV
7% BA-HIV
12% unknown
18.8 86%
Mean missed appts increased from 0.2/yr to 0.3/yr after HCT (p<.001)
NA NA NA NA
Westling, 2016
[10]
(Sweden)
34
91% PA-HIV
19 NA Pre-transfer: 88% prescribed HAART Pre-transfer: 90%
Post-transfer: 92%
NA NA

PA-HIV: perinatally-acquired HIV; BA-HIV: behaviorally acquired HIV; HAART: Highly active antiretroviral therapy; HCT: health care transition

aRetention was defined as the completion of at least two visits over 12 months following linkage to adult care.

bDefinition of post-HCT not defined.

cRetention was defined as at least one physician visit within 6 months of the interview.