Table 2.
Substance use and PrEP-related interactive toxicity beliefs among sexually active MSM who are not and who are PrEP candidates
| Not a PrEP candidate (N = 154) |
PrEP candidate (N = 118) |
|||||
|---|---|---|---|---|---|---|
| Characteristic | N | % | N | % | OR | 95% CI |
| Frequency of alcohol use | ||||||
| None | 16 | 11 | 9 | 8 | Reference | |
| Monthly | 77 | 50 | 61 | 52 | 0.72 | 0.29–1.76 |
| At least weekly | 60 | 39 | 47 | 40 | 1.01 | 0.61–1.68 |
| Quantity of alcohol use | ||||||
| Does not drink | 20 | 13 | 12 | 10 | Reference | |
| 1–2 drinks | 79 | 52 | 49 | 42 | 1.20 | 0.19–7.57 |
| 3–4 drinks | 33 | 22 | 31 | 27 | 1.24 | 0.22–7.02 |
| 5–6 drinks | 15 | 10 | 16 | 13 | 1.88 | 0.32–10.99 |
| 7+ drinks | 6 | 3 | 9 | 8 | 2.13 | 0.34–13.40 |
| Binge drinking | ||||||
| Does not binge drink | 69 | 45 | 34 | 29 | Reference | |
| Binge drinks less than monthly | 48 | 31 | 52 | 44 | 0.57+ | 0.30–1.06 |
| Binge drinks monthly or more | 37 | 24 | 32 | 27 | 1.25 | 0.67–2.31 |
| Drug use in past six months | ||||||
| Cannabis use | 49 | 32 | 55 | 57 | 1.89** | 1.13–3.07 |
| Cocaine use | 13 | 9 | 11 | 10 | 1.11 | 0.48–2.58 |
| Other non-prescription drug use | 4 | 3 | 15 | 13 | 5.46** | 1.76–16.92 |
| PrEP interactive toxicity beliefs | ||||||
| Alcohol and PrEP should never be mixed | 100 | 65 | 68 | 57 | 0.72 | 0.43–1.19 |
| A person should stop taking PrEP if they are drinking |
71 | 47 | 44 | 37 | 0.71 | 0.43–1.16 |
| Alcohol interferes with PrEP so it will not work right |
78 | 53 | 51 | 45 | 0.72 | 0.44–1.19 |
| Mixing alcohol with HIV medications like PrEP is dangerous | 87 | 59 | 60 | 53 | 0.78 | 0.47–1.28 |
| Drinking alcohol while taking PrEP is toxic to the body’s system | 84 | 56 | 57 | 50 | 0.77 | 0.47–1.26 |
Note: OR = odds ratio; CI = confidence interval; MSM = men who have sex with men; PrEP = pre-exposure prophylaxis; +p < .07, **p < .01.