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. 2017 Aug 30;14:18. doi: 10.1186/s12950-017-0165-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Soluble and Insoluble Collagen Changes with MSCs. Whole lung homogenates were obtained from the 4-week chronic asthma model (obtained from the same three studies used for the imaging analysis). Lungs were processed for either soluble (sirius red assay) or insoluble (hydroxyproline Assay). In a and b, the diamond represents a decrease in collagen deposition in response to hMSCs. Each bar is 7 animals representative of a single chronic asthma study (p = 0.06, F variance p = 0.05)