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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Metabolism. 2017 Jun 21;74:32–40. doi: 10.1016/j.metabol.2017.06.006

Figure 5. XO inhibition suppresses WD-induced kidney fibrosis and proteinuria.

Figure 5

A. The bar graph shows increased excretion of protein in WD-fed mice and its prevention of treatment with XO inhibitor. B. WD tended increased fibronectin expression that is decreased by XO inhibition. C. TLR4 receptor expression is increased in WD-fed mice and tended to decrease in XO inhibitor treated group. N =4 to 8 per group. CD - control diet, WD - Western Diet, WDA - Western diet plus allopurinol. Data are expressed as means ± SE. * P<0.05 vs CD; # p<0.05 vs WD.