Table 5.
Differences in LINE-1 methylation levels between cases and controls
| LINE-1 methylation levels | Cases (n = 71) | Controls (n = 68) | p-value a | ||
|---|---|---|---|---|---|
| Median | IQR | Median | IQR | ||
| Site 1 | 70.00 | 21.00 | 66.00 | 17.00 | 0.103 |
| Site 2 | 76.00 | 4.00 | 75.00 | 5.00 | 0.090 |
| Site 3 | 78.00 | 3.00 | 77.00 | 5.00 | 0.032 |
| Mean (all three sites) | 75.00 | 6.00 | 73.17 | 2.92 | 0.002 |
Abbreviations: LINE-1 Long Interspersed Nuclear Element- 1, IQR Interquartile range
aStatistically significant p values (p < 0.05), based on the Mann-Whitney U test, are indicated in bold font