Figure 7.

BMP receptors are required in nociceptive neurons for injury-induced allodynia. Ppk1.9-Gal4>UAS-IR RNAi genotypes targeting Put (A), Sax (B), or Tkv (C) were prepared. Following mock treatment (−) or UV-injury (+), larvae were assayed by gentle touch with a thermal probe set to 41°C. Response latencies were recorded in seconds and categorized as follows: none (>20 s, white area), slow (6–20 s, gray area), and fast (<6 s, black area). Larvae of all three genotypes failed to produce allodynia after injury. Probability of response was compared with control genotypes no-Gal4 (w¹¹¹⁸>UAS-IR) and no-UAS (Ppk1.9-Gal4>y¹v¹) by MLR analysis. Whiskers indicate SEM of at least three groups of larvae; total n = 83–103. ***p < 0.001.