Table 4.
VACS Index, FFI and CES-D individually predict time to all deaths, AIDS deaths and non-AIDS deaths over ~8 years of follow-up among HIV+ women who were ART-experienced.
| All deaths | AIDS deaths | Non-AIDS deaths | |||||||
| Index | χ2 | HR* (95% CI) | p Value | χ2 | HR (95% CI) | p Value | χ2 | HR (95% CI) | p Value |
| VACS score (0–164), per 20 points | 89.81 | 1.82 (1.61 to 2.06) | <0.0001 | 94.95 | 2.52 (2.09 to 3.04) | >0.0001 | 21.22 | 3.27 (1.97 to 5.40) | <0.0001 |
| FFI 3–5 vs 0–2 | 24.70 | 2.35 (1.68 to 3.28) | <0.0001 | 8.44 | 2.27 (1.30 to 3.93) | 0.004 | 6.13 | 1.31 (1.06 to 1.62) | 0.013 |
| CES-D (<16 vs >16) | 0.75 | 1.16 (0.83 to 1.60) | 0.38 | 2.04 | 1.49 (0.86 to 2.59) | 0.15 | 0.17 | 0.90 (0.55 to 1.48) | 0.68 |
| Age per decade | 2.03 | 1.15 (0.95 to 1.39) | 0.15 | 2.88 | 0.77 (0.56 to 1.04) | 0.09 | 7.48 | 1.50 (1.12 to 2.01) | 0.006 |
*Multivariate models included race/ethnicity; education less than or equal to versus greater than high school; smoking current versus no; income less than versus greater than or equal to $12 000 annually; alcohol use: low, moderate or high versus none; and body mass index <30 vs >30 kg/m2 kg/m2.
ART, antiretroviral therapies; CES-D, Center for Epidemiologic Studies-Depression; FFI, Fried Frailty Index; HIV+, HIV-infected; VACS, Veterans Aging Cohort Study.