Table 1.

Model input values and ranges for disease characteristics

Disease state	Prevalence at simulation start				Costs (annual)			Disability weights
	Mean (%)	Min (%)	Max (%)	Ref.	Mean	SD	Ref.	Mean	Min	Max	Ref.
Steatosis	27.955*	18.637	41.933	American Diabetes Association, Wree et al, LaBrecque et al 8 16 18	134	50	Zhang et al 87	0.000	0.000	0.000	Murray et al, Michelotti et al, Page and Harrison88–90
NASH	3.141*	2.094	4.712	American Diabetes Association, Wree et al, LaBrecque et al 8 16 18	267	100	Zhang et al 87	0.033	0.017	0.066	Murray et al, Michelotti et al, Page and Harrison88–90
Cirrhosis	0.314*	0.209	0.471	Foster et al, Farrell and Larter91 92	2861	1073	Baumeister et al 93	0.194	0.127	0.273	10 87
HCC	0.025*	0.017	0.038	Adams et al, Ascha et al 94 95	42 644	15 992	Murray et al, Bambha et al, McAdam-Marx et al 88 96 97	0.294	0.199	0.411	Murray et al, Michelotti et al, Page and Harrison88–90
CHD	6.544*	–	–	Flegal et al, Centers for Disease Control and Prevention1 2 6	13 233	4962	Centers for Disease Control and Prevention, Lightwood et al 6 98	0.066	0.043	0.095	Murray et al 88
T2D	9.447*	–	–	Flegal et al, Centers for Disease Control and Prevention1 2	8170	3064	Lightwood et al, Li et al 98–100	0.150	0.080	0.220	Murray et al, Darbà et al 88 101
Overweight	33.473*	–	–	Flegal et al, Centers for Disease Control and Prevention1 2	343	129	Lightwood et al, Li et al 98 100	0.000	0.000	0.000	Keating et al 102
Obesity	37.391*	–	–	Flegal et al, Centers for Disease Control and Prevention1 2	916	344	Lightwood et al, Li et al 98 100	0.012	0.001	0.022	Keating et al 102

*Age-specific, sex-specific and/or ethnicity-specific values are specified in the online supplement.

CHD, coronary heart disease; HCC, hepatocellular carcinoma; NASH, non-alcoholic steatohepatitis; T2D, type 2 diabetes.

Costs are population based, meaning that they include those who do not get care. CHD, T2D, overweight and obesity prevalence are not varied in the sensitivity analyses.