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. 2017 Jun 9;7(6):e013653. doi: 10.1136/bmjopen-2016-013653

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Cost-effectiveness matrix. Strategy code: (1) standard, (2) hsTnI, (3) hsTnI+LoD, (4) hsTnI+ADP, (5) hsTnI+LoD+ADP, (6) hsTnI+LoD+ADP+direct rule-in. Costs include index costs and 30-day follow-up costs from the hospital perspective. Diagnostic accuracy refers to the adjudicated final diagnosis of acute coronary syndrome within 30 days after presentation to the emergency department. Each data point reflects the strategy specific mean value and 95% CI of 40 000 iterations. ADP, modified ADAPT accelerated diagnostic protocol; hsTnI, high-sensitivity troponin I; LoD, limit of detection.