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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Bioessays. 2017 Aug 9;39(9):10.1002/bies.201700073. doi: 10.1002/bies.201700073

Table 1.

STR/BTR orthologs in model organisms.

Organism Protein
BLM-independent meiotic functions?
BLM TOP3α RMI1 RMI2
S. cerevisiae Sgs1 Top3 Rmi1 N/A Yes [12,40]
A. thaliana RECQ4A/B TOP3α RMI1 RMI2 Yes [20,4143]
M. musculus Blm Top3α Rmi1 Rmi2 unknown
D. melanogaster Blm Top3α N/A N/A unknown
C. elegans HIM-6 TOP-3 RMH-1 N/A Yes [44]

N/A: No ortholog in this species.