. Author manuscript; available in PMC: 2018 Sep 1.

Published in final edited form as: Bioessays. 2017 Aug 9;39(9):10.1002/bies.201700073. doi: 10.1002/bies.201700073

Table 1.

STR/BTR orthologs in model organisms.

Organism	Protein				BLM-independent meiotic functions?
Organism	BLM	TOP3α	RMI1	RMI2	BLM-independent meiotic functions?
S. cerevisiae	Sgs1	Top3	Rmi1	N/A	Yes [12,40]
A. thaliana	RECQ4A/B	TOP3α	RMI1	RMI2	Yes [20,41–43]
M. musculus	Blm	Top3α	Rmi1	Rmi2	unknown
D. melanogaster	Blm	Top3α	N/A	N/A	unknown
C. elegans	HIM-6	TOP-3	RMH-1	N/A	Yes [44]

N/A: No ortholog in this species.