Figure 3.

Comparison of body fat percentage in mice with altered GH action. Male and female bGH mice have greater body fat percent than WT mice earlier in life, a trend that starts to reverse at four and six months of age, respectively (left). Fat percentage is greater in male and female GHA mice compared to controls throughout life. Male GHR-/- mice have markedly increased body fat percent compared to controls and appear to rapidly accumulate fat during the first four months of life. Increased percentage of fat is also observed in female GHR-/- mice compared to controls, albeit not as drastic. Adapted with permission from [38]. Copyright 2017 John Wiley & Son.