Table 2.

MTs and MTs regulatory protein and gene alterations associated with schizophrenia.

Genes/Protein	Effects	Ref.
α-tubulin and β-tubulin	Altered cytoskeletal organization	[100,101,102]
DISC-1	Mutation S704C confers susceptibility to schizophrenia in humans	[110,111]
ULK4	Ulk4−/− mice showed low levels of acetylated α-tubulin	[103]
	ULK4 gene deletions have been found in schizophrenic patients
TTLL 11	Balanced chromosomal translocation combined with chromosomal micro-duplication is associated with increased schizophrenia susceptibility	[104,105]
MAP1B	Low immunoreactivity in hippocampal subiculum associated with altered cyto-architecture and neurotransmission deficits in individuals with schizophrenia	[81,82]
MAP2	Low immunoreactivity in brains of individuals with schizophrenia	[107,108]
MAP6	Neuronal transport defects	[78,109]
	Deletion of gene causes altered mood and cognitive performance in mice models of schizophrenia
ADNP	ADNP protein deregulated in postmortem hippocampi of schizophrenia patients	[112,113]
	ADNP involved in autophagy regulation