. 2017 Aug 3;18(8):1690. doi: 10.3390/ijms18081690

Table 3.

Genotypic distributions of the significant LEPR polymorphisms and its association with obesity by sex in children.

Polymorphism	Allele 1/Allele 2	Case			Control			Minor Allele	Minor Allele		OR (95% CI)	p	p ^a
Polymorphism	Allele 1/Allele 2	11	12	22	11	12	22	Minor Allele	Case	Control	OR (95% CI)	p	p ^a
Females
rs11208659	T/C	113	26	1	72	3	1	C	0.100	0.155	0.56 (0.31–1.00)	0.050	1
rs11804091	A/G	87	42	4	82	19	0	G	0.188	0.094	2.73 (1.47–5.08)	0.001	0.038
rs10157275	C/T	99	37	4	84	17	2	T	0.161	0.102	1.77 (1.01–3.12)	0.045	1
rs9436303	A/G	77	52	11	68	30	5	G	0.264	0.194	1.49 (0.95–2.32)	0.080	1
rs1627238	C/T	93	41	6	75	23	2	T	0.189	0.135	1.59 (0.95–2.32)	0.079	1
rs1327118	G/C	32	73	30	29	54	12	C	0.493	0.411	1.53 (1.01–2.32)	0.048	1
Males
rs11208659	T/C	127	18	1	101	31	1	C	0.068	0.124	0.50 (0.27–0.92)	0.026	0.681
rs11804091	A/G	106	34	4	99	27	2	G	0.146	0.121	1.23 (0.76–2.02)	0.837	1
rs10157275	C/T	96	46	4	100	29	4	T	0.185	0.139	1.40 (0.89–2.21)	0.147	1
rs9436303	A/G	85	48	13	84	43	6	G	0.253	0.207	1.28 (0.87–1.87)	0.218	1
rs1627238	C/T	93	46	7	92	37	3	T	0.206	0.163	1.33 (0.86–2.04)	0.202	1
rs1327118	G/C	41	70	29	33	67	30	C	0.457	0.489	0.88(0.63–1.24)	0.465	1

CI: confidence interval; OR: odds ratio. OR adjusted for age and Tanner stage under the additive model. ^a p values after Bonferroni correction. The bold is the statistic significance for the rows where p is lower than 0.05.