Figure 3.

Spatial learning and memory analysis comparison of C57BL/6 substrains—C57BL/6N and C57BL/6J in scopolamine-induced amnesic model: (a) Step-through passive avoidance test—latency time variance during acquisition and retention; (b) Spontaneous alternation performance (Y-Maze test)—number of arm entries and percentage of alternation (circle dots—control group; square—scopolamine group; triangle represents tacrine group). Tacrine (10 mg/kg) was used as positive control. Data are expressed as mean ± SD (n = 5). One-way ANOVA-Tukey’s multiple comparison test was performed where, * p < 0.05 scopolamine compared with the control group; ^$ p < 0.05 tacrine compared with scopolamine-treated group.