Table 6.
Sensitivities corresponding with particular drugs (wherever ≥5 SJS/TEN patients were tested with the same method).
Drug | Method | Patients | Sensitivity | ||
---|---|---|---|---|---|
Performed Tests | Performed Tests | ||||
aAEDs | proliferation | LTT | 29 | 14 | 0.48 |
aAEDs (1) | Grl in CD3+CD4+ | FACS | 9 | 5 | 0.56 |
GrB | ELISpot | 9 | 3 | 0.33 | |
IFNg | CBA | 7 | 4 | 0.57 | |
ALP/OXP | proliferation | LTT | 5 | 1 | 0.20 |
IFNg | ELISpot | 12 | 8 | 0.67 | |
ALP/OXP (1) | Grl | ELISA | 7 | 6 | 0.86 |
Sulphonamides | proliferation | LTT | 5 | 1 | 0.20 |
(1) based on data from a single study, abbreviations: as in Table 1. Data for specificity not available (Results for particular drugs not reported in control groups in most studies).