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. 2017 Aug 11;18(8):1747. doi: 10.3390/ijms18081747

Table 1.

Theoretical binding sites for transcription factors involved in stress-response and transcriptional regulation from the promoter region of Biomphalaria glabrata. Abbreviated terms indicate the binding sites and suggested functional context according to explanations in TRANSFAC databases (see materials and methods).

Response Elements and Binding Sites for Transcription Factors Involved in Stress Response
Response element or binding site (abbreviation) Explanation Functional context
C/EBP C/Enhancer binding protein Glucocorticoid activation
HSE Heat Shock element Heat shock protein activation
MRE Metal responsive element Metal-induced expression
PPAR Peroxisome proliferator activated receptor Stress response
YAP Yeast activator protein Multidrug resistance in yeast [34]
Response Elements and Binding Sites for Transcription Factors Involved in Transcriptional Regulation
Response element or binding site (abbreviation) Explanation Functional context
AP-1 Activator Protein 1 Nuclear transcriptional activator
ATF Activating transcription factor Transcriptional activator
cMyc c-myc protein Telomerase activator
GATA-1 GATA binding protein 1 Cell growth transcription factor
POU1F1a, POU2F1 Octamer-binding factors Transcriptional activators
p300 E1A-associated 300-kDa protein Transcriptional enhancer
PBF Prolamin box binding factor Transcriptional activator in plants
TBP TATA-binding protein Polymerase activator
Cdx-1 Cdx homeodomain protein Activator
MEF-2C MADS box transcription enhancer factor 2 Transcriptional enhancer