Figure 5.

AI improves the hepatic insulin signaling pathway in mice. (A) Fasting plasma levels of insulin and glucose and homeostasis model assessment of basal insulin resistance (HOMA-IR)) index; (B) oral glucose tolerance test (OGTT) and area under the curve (AUC); (C) densitometric quantification of the phosphorylation of IRS1, AKT, FOXO, and ApoB100 in the liver; (D) hepatic expression of genes involved in VLDL assembly; Statistical analysis was performed using one-way ANOVA and analyzed further by Duncan’s multiple range test. Different letters above the bars indicate significant differences among experimental groups (p < 0.05).