ABC |
ATP-binding cassette |
[Ca2+]c
|
Cytosolic Ca2+ concentration |
CF |
Cystic fibrosis |
CFRD |
CF-related diabetes |
CFTR |
Cystic fibrosis transmembrane conductance |
[Cl−]i
|
Intracellular Cl− concentration |
ΔF508 |
Deletion of phenylalanine at position 508 |
DM |
Diabetes mellitus |
ENaC |
Epithelial Na+ channel |
GLUT |
Glucose transporter |
MSD |
Membrane-spanning domains |
MQAE |
N-(ethoxycarbonylmethyl)-6-methoxyquinolinium bromide |
NBD |
Nucleotide binding domains |
NCC |
Na+-Cl− cotransporter |
NKCC |
Na+-K+-2Cl− cotransporter |
PI3K |
Phosphoinositide 3-kinase |
RD |
Regulatory domain |
TM |
Transmembrane |
VDCCs |
Voltage-dependent Ca2+ channels |