Table 5.
Top five new DTIs predicted by DAWN on four data sets.
| Dataset | Rank | Drug | Target | Databases |
|---|---|---|---|---|
| Enzyme | 1 | D00545 | hsa1571 | |
| 2 | D03365 | hsa1571 | ||
| 3 | D00437 | hsa1559 | M | |
| 4 | D00546 | hsa1571 | ||
| 5 | D00184 | hsa5478 | D | |
| Ion channel | 1 | D00542 | hsa6262 | |
| 2 | D00542 | hsa6263 | M | |
| 3 | D00349 | hsa6263 | ||
| 4 | D00477 | hsa6336 | C | |
| 5 | D01448 | hsa3782 | ||
| GPCR | 1 | D01051 | hsa3269 | |
| 2 | D00563 | hsa3269 | D, M | |
| 3 | D00563 | hsa1812 | D | |
| 4 | D00715 | hsa1129 | D, K | |
| 5 | D00563 | hsa1129 | ||
| Nuclear receptor | 1 | D01689 | hsa5241 | |
| 2 | D01115 | hsa5241 | ||
| 3 | D00443 | hsa5241 | D | |
| 4 | D00443 | hsa367 | D | |
| 5 | D00187 | hsa2099 |
C: ChEMBL; D: DrugBank; K: KEGG; M: Matador.