Figure 5.

Mitochondrial structure-function relations as a function of substrate stiffness. VSMCs were seeded on substrates of different stiffness, labeled with TMRM, and cluster sizes and mean intensities were measured. The horizontal lines in the boxes are the median, the box represents the 25th percentile, and the horizontal bars are the 75th percentile of the data. The symbols are data outside the 75th percentile. (A) Cluster sizes were stiffness dependent, but only the clusters on 12.5 kPa stiffness were different from the rest. (B) Intensities were also stiffness dependent, and again only data on 12.5 kPa stiffness were different from the rest.