Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug 22;18(8):1821. doi: 10.3390/ijms18081821

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Summary of factors mentioned in the text that are associated with instability of mammalian mitochondrial DNA. The list presented herein is not exhaustive. (Polγ: polymerase γ, mtSSB: mitochondrial single stranded DNA binding protein, TFAM: mitochondrial transcription factor A, NRF1/2: nuclear respiratory factors 1 and 2, PrimPol: primase-polymerase; Pif1: petite integration frequency 1, BER: base excision repair, Mfn: mitofusin, Opa1: optic atrophy protein 1,Drp1: dynamin related protein 1,hFIS1: fission 1 protein, Mff: mitochondrial fission factor, MiD49/51: mitochondrial dynamics proteins of 49 and 51 kDa, RRM2B: ribonucleoside-diphosphate reductase subunit M2 B).