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Proposed effects of miR-30a-5p on UTUC. The miR-30a-5p-enhanced CLDN-5 expression may trigger tight junction pathway signal transduction. Moreover, miR-30a-5p suppresses the EMT process via increasing E-cadherin and suppressing vimentin, fibronectin, and α-SMA expression, thereby inhibiting the migration activity of UTUC cells.
