Table 1.
Result of pathway enrichment analysis on the 259 downregulated genes. We identified 19 significant pathways, the p-values, pathway names, and KEGG pathway IDs of which are provided.
| Pathway Name | p-Value | Pathway ID |
|---|---|---|
| MAPK signaling pathway | 0.00274259 | kegg_pathway_261 |
| PI3K-Akt signaling pathway | 0.00308062 | kegg_pathway_262 |
| Tight junction | 0.00451891 | kegg_pathway_257 |
| Protein digestion and absorption | 0.00458404 | kegg_pathway_279 |
| Notch signaling pathway | 0.00534759 | kegg_pathway_55 |
| Cytokine-cytokine receptor interaction | 0.00924043 | kegg_pathway_79 |
| Endocytosis | 0.0151682 | kegg_pathway_232 |
| Focal adhesion | 0.0158629 | kegg_pathway_188 |
| Regulation of actin cytoskeleton | 0.0164765 | kegg_pathway_139 |
| Morphine addiction | 0.0191389 | kegg_pathway_101 |
| Calcium signaling pathway | 0.022008 | kegg_pathway_237 |
| Amoebiasis | 0.0234208 | kegg_pathway_214 |
| Amino sugar and nucleotide sugar metabolism | 0.0254128 | kegg_pathway_203 |
| GABAergic synapse | 0.0258019 | kegg_pathway_235 |
| Ras signaling pathway | 0.0265302 | kegg_pathway_265 |
| Endocrine and other factor-regulated calcium reabsorption | 0.0266089 | kegg_pathway_174 |
| HTLV-I infection | 0.0280212 | kegg_pathway_190 |
| ECM-receptor interaction | 0.0314539 | kegg_pathway_242 |
| Jak-STAT signaling pathway | 0.0400457 | kegg_pathway_40 |