Figure 7.
Wound closure in diabetic rats for subjects treated with (A) GAG (glycosaminoglycan)-PA (Peptide amphiphiles)/K-PA (also known as positively charged heparin mimetic PAs), (B) PBS control, and (C) E-PA (negatively charged heparin mimetic PA)/K-PA. (D) shows the schematic diagram for the location of wound on the rats that were treated with GAG-PA/K-PA, PBS and E-PA/K-PA samples. (E) Shows the % wound closure studied for 14 days after the treatment. It can be seen that after 14 days of the treatment compared to control. It can be seen that GAG-PA/K-PA bio gel-treated group provided significant wound healing property on 14th day of treatment, compared to the E-PA/K-PA- or PBS-treated control groups (one way ANOVA test with * p < 0.05, ** p < 0.01, *** p < 0.001). Reproduced with permission from [150].
