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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Obstet Gynecol. 2017 Sep;130(3):511–519. doi: 10.1097/AOG.0000000000002199

Table 3.

Hypoxic and traumatic neonatal morbidity and growth

SGA (N=4,983) AGA N=53,200) LGA (N=5,253)
n (%) uRR* (95% CI) aRR (95% CI) n (%) n (%) uRR* (95% CI) aRR (95% CI)
Hypoxic composite neonatal morbidity 55 (1.1) 1.57 (1.18-2.08) 1.44 (1.07-1.93)§ 374 (0.7) 31 (0.6) 0.84 (0.58-1.21) 0.84 (0.58-1.22)
Traumatic composite neonatal morbidity 65 (1.3) 1.33 (1.03-1.72) 1.28 (0.98-1.67) 523 (1.0) 102 (1.9) 1.98 (1.60-2.44) 1.88 (1.51-2.34)
 Bronchopulmonary dysplasia H 0 (0.0) 2 (0.0) 1 (0.0)
 Persistent pulmonary hypertension of the newborn H 11 (0.2) 36 (0.1) 9 (0.2)
 Proven newborn sepsis H 6 (0.1) 44 (0.1) 5 (0.1)
 Necrotizing enterocolitis stage II or III H 0 (0.0) 3 (0.0) 0 (0.0)
 Intraventricular hemorrhage grade (IVH) III or IV H 0 (0.0) 1 (0.0) 0 (0.0)
 Apgar score < 5 at 5 min H, T 19 (0.4) 93 (0.2) 6 (0.1)
 Ventilator support within 24 hrs. H, T 25 (0.5) 191 (0.4) 16 (0.3)
 Seizure H, T 7 (0.1) 39 (0.1) 3 (0.1)
 Cardiopulmonary resuscitation within first 24 hrs. H, T 7 (0.1) 30 (0.1) 2 (0.0)
 Hypoxic ischemic encephalopathy H, T 20 (0.4) 92 (0.2) 9 (0.2)
 Death before discharge H, T 3 (0.1) 7 (0.0) 2 (0.0)
 Fracture (skull, depressed skull, clavicle, other) T 6 (0.1) 135 (0.3) 54 (1.0)
 Intracranial hemorrhage (other than IVH) T 7 (0.1) 70 (0.1) 4 (0.1)
 Brachial plexus injury T 1 (0.0) 24 (0.1) 19 (0.4)
 Facial nerve palsy T 3 (0.1) 5 (0.0) 2 (0.0)

 Data as n (%)

SGA, small for gestational age; AGA, appropriate gestational age; LGA, large for gestational age; aRR, adjusted relative risk; CI, confidence interval

H

—a component of hypoxic CNM;

T

—a component of traumatic CNM

*

Compared with AGA and unadjusted

Compared with AGA and adjusted for insurance status, nulliparity, body mass index, and male fetal sex; number with complete data in the multivariable model is 61905

P=.002

§

P=.02

P=.03

P<.001