Table 4.

Regression analysis association between maternal PFC serum concentrations and earlier age at menarche, unadjusted and controlling for birth order and maternal age at delivery.

Analyte	Continuous		Binary
	Unadjusted	Adjusted	Unadjusted	Adjusted
	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)
PFOSA	0.89 (0.66–1.20)	0.91 (0.67–1.24)	0.82 (0.57–1.19)	0.85 (0.58–1.25)
Sulfonamide esters	0.90 (0.64–1.25)	0.91 (0.65–1.28)	0.76 (0.52–1.11)	0.78 (0.53–1.14)
Et-PFOSA-AcOH	1.02 (0.75–1.40)	1.03 (0.75–1.43)	1.17 (0.81–1.70)	1.17 (0.80–1.72)
Me-PFOSA-AcOH	0.86 (0.67–1.11)	0.86 (0.66–1.12)	0.85 (0.58–1.24)	0.85 (0.57–1.25)
Sulfonates	0.82 (0.52–1.30)	0.66 (0.40–1.08)	0.83 (0.57–1.20)	0.74 (0.50–1.09)
PFOS	0.85 (0.53–1.36)	0.68 (0.40–1.13)	0.92 (0.63–1.33)	0.83 (0.56–1.23)
PFHxS	1.00 (0.74–1.33)	0.89 (0.65–1.22)	1.17 (0.81–1.70)	1.11 (0.76–1.64)
Carboxylates	1.21 (0.76–1.95)	0.98 (0.58–1.66)	1.35 (0.93–1.96)	1.25 (0.84–1.88)
PFOA	1.25 (0.79–1.95)	1.01 (0.61–1.68)	1.35 (0.93–1.96)	1.29 (0.86–1.93)
PFNA	1.00 (0.66–1.52)	0.91 (0.59–1.40)	1.28 (0.88–1.86)	1.15 (0.78–1.69)

Continuous represents natural log transformed values (values below the LOD are substituted with √LOD/2), while binary represents at or above the median value among cases, versus below the median value among cases. PFDeA is not included in the summed value if it was below the LOD.